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Hypnotic doses of these barbiturates do not look to appreciably impair uterine activity throughout labor; total anesthetic doses of barbiturates lessen the force and frequency of uterine contractions; administration of sedative-hypnotic barbiturates to the mom all through labor may perhaps bring about respiratory despair in the newborn
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pentobarbital will lower the level or outcome of bedaquiline by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Stay clear of coadministration of bedaquiline with robust CYP3A4 inducers resulting from possible for lowered therapeutic result
pentobarbital will lessen the level or effect of lapatinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
pentobarbital will decrease the level or outcome of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
pentobarbital will minimize the extent or impact of darunavir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
Opportunity for Wrong constructive check outcomes if macimorelin and powerful CYP3A4 inducers are coadministered. Discontinue sturdy CYP3A4 inducer, making it possible for for ample washout time, ahead of testing.
pentobarbital decreases outcomes of hemin by pharmacodynamic antagonism. Use Caution/Observe. Medications that improve delta-aminolevulinic acid synthetase may decrease hemin influence.
Contraindicated (one)pentobarbital will lower the extent or result of lumacaftor/ivacaftor by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will decrease the level or impact of gefitinib by check here influencing hepatic/intestinal enzyme CYP3A4 metabolism.
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Watch Carefully (two)pentobarbital will reduce the level or effect of suvorexant by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check. Strong CYP3A4 inducers may possibly minimize suvorexant efficacy; if enhanced suvorexant dose required, never exceed 20 mg/working day
pentobarbital will reduce the level or outcome of doravirine by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will lower the extent or impact of disopyramide by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Mysterious.